New paper on actin regulation via energy status published in PNAS

The actin cytoskeleton is constantly remodelled during daily activity of a cell. However, this remodelling requires a constant input of cellular energy in the form of ATP. Our collaboration with Yi Zhang’s group at Beijing Normal University is now available online with PNAS.

This work reports that the TOR complex, a master regulatory hub that integrates cellular energy information to coordinate cell growth and metabolism, controls cellular ATP levels in plant cells. Interestingly, low ATP levels cause reduced actin dynamics in plant cells, providing insight into how plant cells handle low energy situations.

https://doi.org/10.1073/pnas.2004822117